Nootropics for Alzheimer’s Disease

Nootropics, referred to as smart drugs and cognitive enhancers, are one of the significant medical innovations. These supplements are used to improve cognition and boost memory. the doctors closet provides some information on nootropics related to daily use, and alleviating depression and anxiety. These drugs are also used primarily to aid in the treatment of cognitive or motor function difficulties related to disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and ADHD.

Alzheimer’s disease and nootropics

Alzheimer’s disease is a chronic neurodegenerative disease affecting elderly population. Early stage of disease is characterized by the impairment of recent memory followed by impairment of cognitive abilities. Nootropics cannot cure Alzheimer’s disease, but can improve memory and cognition in older people. Further, they may also have neuroprotective effect and can aid in treatment. Nootropics are available as natural herbal supplements (Bacopa monnieri, Panax ginseng, and Gingko biloba) or synthetic drugs, such as racetams (e.g. piracetam). Herbal medications are being used more commonly because they are found to be safer than their synthetic counterparts.

Bacopa monnieri

It is an herbal nutraceutical and is known for its role as nootropic agent in Ayurveda and is referred to as “Brahmi” in India. Various indications of Brahmi in Ayurvedic medicine are epilepsy, anxiolytic, memory improvement, and insomnia. Regarding memory improvement, it works by lessening the amnesiainstead of increasing learning. It has shown to improve memory performance and cognitive function in several studies conducted on humans and animals. It exerts multiple effects on central nervous system, including neuronal and glial plasticity, β-amyloid, cerebral blood flow, and cholinergic system, all of which contribute to healthy nervous system. It also has antioxidant and iron chelating properties, essential for reducing age-related illnesses. For Alzheimer’s disease, Brahmi is administered as either capsule in doses of 250-500 mg or Churna in doses of 1-2 g once or twice a day. The side-effects are mild, most commonly reported ones are nausea, gastrointestinal upset, and intestinal hypermotility.